Horny Jo’s Daily Blog

gollum123 writes “A major advance in the genetic understanding behind several of the world’s most common diseases is being reported by the BBC. A study tested some 17,000 people to find genetic markers for the various diseases. ‘They found new genetic variants for depression, Crohn’s disease, coronary heart disease, hypertension, rheumatoid arthritis and type 1 and 2 diabetes. The Wellcome Trust Case Control Consortium (WTCCC) involved 50 leading research groups analyzing the DNA from 2,000 patients for each of the seven conditions and 3,000 healthy volunteers. One of the most exciting finds was a previously unknown gene common to type 1 diabetes and Crohn’s disease, a type of inflammatory bowel disorder, suggesting that they share similar biological pathways.’ There is also disease by disease data at the BBC.”

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anik315 writes “Nature is reporting a major breakthrough in embryonic stem cell research. A straightforward procedure using mouse fibroblasts harvested from the skin can be used to produce pluripotent stem cells that can potentially become any other cell in the body. Not only can Yamanaka’s method use the most basic cells, it can be accomplished with simple lab techniques. Possible applications of this breakthrough are to check molecular changes in cells as certain conditions develop. Stem cells produced using this procedure, however, can not be use to safely to make genetically matched cells for transplant.”

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